Intrauterine Insemination (IUI)

Intrauterine Insemination (IUI) – What is it?

Intrauterine insemination (IUI) is one of the most commonly used methods in medically assisted reproduction. It is a simple, minimally invasive, and cost-effective procedure that offers promising success rates in the right cases.

When Is IUI Recommended?

IUI is typically recommended when infertility is mild or unexplained, and may be appropriate in the following situations:

• Mild male infertility (low sperm count or reduced motility)
• Erectile dysfunction or ejaculation problems
• History of testicular surgery, radiation, or chemotherapy
• Ovulatory disorders or irregular menstrual cycles
• Cervical mucus problems
• Use of donor sperm

Additionally, IUI is most effective when the woman:

• Is under 35 years old
• Has a normal hormonal profile
• Has at least one open fallopian tube

IUI Procedure: Step by Step

1. Ovulation Monitoring
   The woman may take fertility medication to stimulate ovulation. Ultrasounds are used to monitor follicle development. When the follicle is mature, ovulation is triggered, usually 24–36 hours before the procedure.
2. Sperm Preparation
   On the day of insemination, a semen sample is collected and processed in the lab to isolate motile, healthy sperm, removing immobile or abnormal ones.
3. Insemination
   A thin, flexible catheter is used to place the prepared sperm directly into the uterus. The procedure is quick and painless, typically lasting just a few minutes.
4. Post-Procedure
   After insemination, the woman lies down for about 30 minutes, after which she can return to her daily activities. There’s no recovery time needed and no restrictions that could affect the success of the process.

Success Rates of IUI

Success rates for IUI range from 15% to 18% per cycle, depending on:

• The woman’s age
• The cause of infertility
• Hormonal and uterine factors

In many cases, 3 or more cycles may be needed to significantly increase the chance of pregnancy.

IUI vs IVF: What’s the Difference?

• IUI is often a first-line treatment for younger women with mild infertility or hormonal imbalance.
• IVF is generally recommended for more complex cases, including:
  • Blocked fallopian tubes
  • Recurrent miscarriages
  • Severe male infertility
  • Advanced endometriosis
  • Ovarian insufficiency

While IUI has a 15–18% success rate, IVF success rates can reach 35–40% per cycle, especially for women aged 30–35. It’s essential to consult with a fertility specialist to determine the most suitable path forward and avoid unnecessary delays.

IUI – Frequently Asked Questions