Many women feel hesitant about undergoing in vitro fertilization (IVF), often due to concerns about the medications involved. As a result, a more natural, less invasive alternative—Mini IVF—is becoming an increasingly popular choice for women seeking fertility support without extensive hormone stimulation.
What is Mini IVF?
Mini IVF, also known as micro-IVF, follows the same core steps as conventional IVF but involves minimal ovarian stimulation.
- In most cases, no injections are required—or far fewer than with standard IVF.
- Medications are usually taken orally.
- The goal is to gently stimulate the ovaries to produce a small number (3 to 5) of high-quality eggs in a single cycle.
Unlike conventional IVF, which aims to collect 7 to 15 eggs, many of which may not be viable, Mini IVF focuses on quality over quantity. Studies suggest that eggs retrieved through this gentler approach may result in higher-quality embryos.
Importantly, international medical literature shows that women with poor ovarian response may benefit more from low-dose stimulation protocols—like Mini IVF—than from high-dose medication.
Who is Mini IVF recommended for?
Mini IVF may be the ideal option for women who:
- Prefer to avoid or minimize fertility medications
- Are over the age of 42, or are younger with hormonal imbalances or low ovarian reserve
- Have a history of cancer, or are preparing for cancer treatment
- Seek a more affordable IVF option
- Are at high risk for ovarian hyperstimulation syndrome (OHSS)
What are the advantages of Mini IVF?
- Reduced use of fertility medications
- Lower cost compared to conventional IVF
- Virtually no risk of ovarian hyperstimulation
- Reduced risk of multiple pregnancies
- Higher chances of pregnancy compared to natural conception or a natural IVF cycle, due to a slightly increased number of eggs retrieved
What are the success rates of Mini IVF?
According to international studies, Mini IVF success rates can reach 30–35% per embryo transfer, especially in women over 40 years old. While results vary by age and individual circumstances, this approach offers promising outcomes in selected cases—with fewer medications and less physical and emotional strain.